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GLP-1 · Reconstitution Calculator

Tirzepatide Calculator

GLP-1 / GIP dual agonist

Calculate weekly dose volume and U-100 units for every titration step

Tirzepatide is a dual GLP-1 / GIP agonist dosed weekly, starting at 2.5 mg and titrating up monthly to 5, 7.5, 10, 12.5, or 15 mg as tolerated. With six titration steps, the math gets repetitive fast — this calculator handles each step instantly. Enter your vial size and bacteriostatic water volume once, then adjust the dose as you climb the ladder.

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Interactive Tirzepatide reconstitution and dose calculator

Worked example — Tirzepatide 2.5 mg starting dose

A typical reconstitution and dose calculation for Tirzepatide, with every variable spelled out. The calculator above runs the same math live as you change inputs.

Vial strength
20 mg
Bacteriostatic water
3 mL
Concentration
6.67 mg/mL
Dose volume
0.375 mL · 37.5 units

A 20 mg Tirzepatide vial reconstituted with 3 mL of bacteriostatic water yields 6.67 mg/mL. A 2.5 mg starting dose is 0.375 mL — about 37 to 38 units on a U-100 syringe. At the 15 mg maintenance dose, you would draw 2.25 mL, which exceeds a single 1 mL syringe — split across multiple injections or reconstitute with a smaller water volume to concentrate.

Tirzepatide dosing FAQs

Answers to the questions patients and clinicians ask most often about Tirzepatide.

Related peptide calculators

Pre-loaded calculators for peptides commonly stacked or compared with Tirzepatide.

Need a Tirzepatide protocol from a licensed provider?

The calculator handles the math. A licensed CULTR Health provider reviews your goals, lab history, and current medications before prescribing a peptide protocol that fits you. Telehealth visits are available only to eligible patients physically located in Florida.

This Tirzepatide calculator is an educational tool. It does not replace medical advice, prescription, or supervision. Compounded peptides are dispensed only by licensed 503A and 503B pharmacies under a valid prescription.